Download Ciba Foundation Symposium 39 - Monoamine Oxidase and its by Mary L. C. Bernheim(auth.) PDF

By Mary L. C. Bernheim(auth.)

Chapter 1 advent (pages 1–4): S. S. Kety
Chapter 2 the character and destinations of the a number of types of Monoamine Oxidase (pages 5–31): okay. F. Tipton, M. D. Houslay and T. J. Mantle
Chapter three The motion of Acetylenic Inhibitors on Mitochondrial Monoamine Oxidase: constitution of the Flavin website within the Inhibited Enzyme (pages 33–47): A. L. Maycock, Robert H. Abeles, J. I. Salach and Thomas P. Singer
Chapter four Cysteinyl Flavin in Monoamine Oxidase from the valuable apprehensive procedure (pages 49–59): J. I. Salach, T. P. Singer, ok. T. Yasunobu, N. Minamiurat and M. B. H. Youdim
Chapter five Monoamine Oxidase Inhibitors and the Transformation of Monoamine Oxidases (pages 61–81): V. Z. Gorkin
Chapter 6 dietary necessities for Amine Metabolism in vivo (pages 83–103): Theodore L. Sourkes and Krystyna Missala
Chapter 7 Physiological points of the Oxidative Deamination of Monoamines (pages 105–133): M. B. H. Youdim and Margarethe Holzbauert
Chapter eight research of the Pharmacological results of Selective Monoamine Oxidase Inhibitors (pages 135–161): J. Knoll
Chapter nine using Selective Monoamine Oxidase Inhibitor medicines for comparing Pharmacological and Physiological Mechanisms (pages 163–179): Norton H. Neff and Jose A. Fuentes
Chapter 10 The half performed by way of Mono Amine Oxidase within the Inactivation of Catecholamines in Intact Tissues (pages 181–201): U. Trendelenburg, ok. H. Graefe and M. Henseling
Chapter eleven Can the Intra? and Extra?Homoneuronal Metabolism of Cate?Cholamines be distinct within the Mammalian imperative worried procedure? (pages 203–229): D. F. Sharman
Chapter 12 Use of a Behavioural version to review the motion of Monoamine Oxidase Inhibition in vivo (pages 231–245): A. Richard eco-friendly and Moussa B. H. Youdim
Chapter thirteen family members among the measure of Monoamine Oxidase Inhibition and a few Psychopharmacological Responses to Monoamine Oxidase Inhibitors in Rats (pages 247–270): L. Mai?tre, A. Delini?Stula and P. C. Waldmeier
Chapter 14 advent to medical points of Monoamine Oxidase Inhibitors within the remedy of melancholy (pages 271–296): C. M. B. Pare
Chapter 15 the connection among category and reaction to medicinal drugs in Affective Disorders—Problems Posed through Drug reaction in Affective issues (pages 297–325): M. Roth, C. Gurney, C. Q. Mountjoy, T. A. Kerr and ok. Schapira
Chapter sixteen adaptations in Monoamine Oxidase task in a few Human illness States (pages 327–340): M. Sandler
Chapter 17 scientific, Genetic, Hormonal and Drug impacts at the task of Human Platelet Monoamine Oxidase (pages 341–351): Dennis L. Murphy
Chapter 18 An research of Platelet Monoamine Oxidase task in Schizophrenia and Schizoaffective Psychosis (pages 353–388): I. Brockington, T. J. Crow, Eve C. Johnstone and F. Owen
Chapter 19 end (pages 389–391): S. S. Kety

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Additional resources for Ciba Foundation Symposium 39 - Monoamine Oxidase and its Inhibition

Sample text

It appears from these experiments that the substrate, benzylamine, protects from irreversible inactivation not because it reduces the enzyme but because it competes effectively with dimethylpropargylamine for the active site, preventing effectively its enzymic conversion to the form capable of producing irreversible inhibition. This is also seen in Fig. 003 mM-benzylamine should suffice to reduce the enzyme, for extensive protection against the inhibitor the presence of nearly 100 times more benzylamine was required.

Pharmacol. 17, 1285-1297 LAL,S. L. (1970) The effect of chronic administration of carbon tetrachloride and alpha-naphthylisothiocyanate o n tissue copper levels in the rat. Biochem. Med. 4 , 260-276 NATURE AND LOCATIONS OF THE MULTIPLE FORMS OF M A 0 31 MCCAULEY, R. & RACKER, E. (1973) Separation of two monoamine oxidases from bovine brain. Mol. Cell. Biochem. 1, 73-81 MURPHY, D. , DONNELLY, C. H. & RICHELSON, E. (1976) Substrate and inhibitor-related characteristics of monoamine oxidase in C6 rat glial cells.

Arch. Biochem. Biophys. 139, 320-328 HOUSLAY,M. D. & TIPTON,K . F. (1973) The nature of the electrophoretically separable multiple forms of rat liver monoamine oxidase. Biochem. J. 135, 173-186 HOUSLAY, M. D. & TIPTON, K . F. (1974) A kinetic evaluation of monoamine oxidase activity in rat liver rnitochondrial outer membranes. Biochem. J. 139, 645-652 HOUSLAY, M. D. & TIPTON, K. F. (1975) Amine Competition for oxidation by rat liver mitochondrial monoamine oxidase. Biochem. Pharmacol. 24, 627-63 1 JARROTT, B.

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